Compile Data Set for Download or QSAR

Found 2484 hits of ic50 data for polymerid = 1085,50001159   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576014 (CHEMBL4521249) Show SMILES O=c1c(-c2ccc3ncccc3c2)c(Nc2cc[nH]n2)[nH]c2c(c(nn12)-c1ccccc1)C1=CCCCC1 |t:38| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576017 (CHEMBL4552959) Show SMILES CCOC(=O)c1nnc(Nc2[nH]c3c(c(nn3c(=O)c2-c2ccc3ncccc3c2)-c2ccccc2)-c2ccccc2)o1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50598619 (CHEMBL5199008) Show SMILES CCOc1ncc2cc(C3=CC4N=C(CCN5CCC(O)C5)N(C)C4C=C3)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 |c:27,t:9,12| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00395 BindingDB Entry DOI: 10.7270/Q28G8QRH
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576013 (CHEMBL4558617) Show SMILES COc1ccc(cc1)-c1c(Nc2cc[nH]n2)[nH]c2c(c(nn2c1=O)-c1ccccc1)C1=CCCCC1 |t:35| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576011 (CHEMBL4514699) Show SMILES Oc1ccc(cc1)-c1c(Nc2cc[nH]n2)[nH]c2c(c(nn2c1=O)-c1ccccc1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576015 (CHEMBL4582312) Show SMILES O=c1c(-c2ccc3ncccc3c2)c(Nc2cc[nH]n2)[nH]c2c(c(nn12)-c1ccccc1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576019 (CHEMBL4568226) Show SMILES COc1ccc(cc1)-c1c(Nc2ccccn2)[nH]c2c(c(nn2c1=O)-c1ccccc1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50575978 (CHEMBL4860456) Show SMILES Cc1nn2c([nH]c(C)cc2=O)c1-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00395 BindingDB Entry DOI: 10.7270/Q28G8QRH
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50575996 (CHEMBL4870597) Show SMILES Cc1[nH]c2c(N3CCCCC3)c(nn2c(=O)c1-c1ccc2OCOc2c1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576018 (CHEMBL4585665) Show SMILES COc1ccc(cc1)-c1c(Nc2ccon2)[nH]c2c(c(nn2c1=O)-c1ccccc1)C1=CCCCC1 |t:35| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50604362 (CHEMBL5185760) Show SMILES CCNc1ccc2cn(-c3ccc4nn(C)cc4c3)c(=O)c(-c3ccc(Cl)cc3)c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01595 BindingDB Entry DOI: 10.7270/Q28K7F57
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50604357 (CHEMBL5177250) Show SMILES Cn1cc2cc(ccc2n1)-n1cc2ccc(NCC(F)(F)F)nc2c(-c2ccc(Cl)cc2)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01595 BindingDB Entry DOI: 10.7270/Q28K7F57
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576016 (CHEMBL4584451) Show SMILES CCOC(=O)n1ccc(Nc2[nH]c3c(c(nn3c(=O)c2-c2ccc(OC)cc2)-c2ccccc2)-c2ccccc2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50604360 (CHEMBL5187048) Show SMILES Cn1cc2cc(ccc2n1)-n1cc2ccc(OCC(F)F)nc2c(-c2ccc(Cl)cc2)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01595 BindingDB Entry DOI: 10.7270/Q28K7F57
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576012 (CHEMBL4559088) Show SMILES COc1ccc(cc1)-c1c(Nc2cc[nH]n2)[nH]c2c(c(nn2c1=O)-c1ccccc1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581712 (CHEMBL5078281) Show SMILES CCN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637532 ((3-amino-6-((1rs,2RS,3SR)-2,3- dimethylcyclopropyl...) Show SMILES COc1ccccc1C(=O)n1nc(N)c2ccc(nc12)[C@@H]1[C@@H](C)[C@H]1C |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50604356 (CHEMBL5178902) Show SMILES Cn1cc2cc(ccc2n1)-n1cc2cnc(NCC(F)(F)F)nc2c(-c2ccc(Cl)cc2)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01595 BindingDB Entry DOI: 10.7270/Q28K7F57
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576021 (CHEMBL4573938) Show SMILES COc1ccc(cc1)-c1c(Nc2ccccn2)[nH]c2c(c(nn2c1=O)-c1ccccc1)C1=CCCCC1 |t:36| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581709 (CHEMBL5075691) Show SMILES CN(C)c1nc(=O)n(-c2cccc(C)c2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637564 ((3-amino-6-cyclopropyl-1H- pyrazolo[3,4-b]pyridin-...) Show SMILES Nc1nn(C(=O)c2cccnc2Cl)c2nc(ccc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637523 (US20230382911, Example 35 | [3-amino-6-(2,5-dihydr...) Show SMILES COc1ccccc1C(=O)n1nc(N)c2ccc(nc12)C1=CCOC1 |t:23| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581713 (CHEMBL5085027) Show SMILES CCN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637556 ((3-amino-6-cyclopropyl-1H- pyrazolo[3,4-b]pyridin-...) Show SMILES Cc1ncccc1C(=O)n1nc(N)c2ccc(nc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637511 (US20230382911, Example 23 | [3-amino-6-(cyclopente...) Show SMILES COc1ccccc1C(=O)n1nc(N)c2ccc(nc12)C1=CCCC1 |t:23| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50598622 (CHEMBL5181969) Show SMILES CCOc1ncc2cc(-c3ccc4ncn(C)c4c3)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00395 BindingDB Entry DOI: 10.7270/Q28G8QRH
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581711 (CHEMBL5078692) Show SMILES CN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50604355 (CHEMBL5207988) Show SMILES Cc1nc2ccc(cc2n1C)-n1cc2cnc(NCC(F)(F)F)nc2c(-c2ccc(Cl)cc2)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01595 BindingDB Entry DOI: 10.7270/Q28K7F57
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50604348 (CHEMBL5170690) Show SMILES COc1ccc(cc1)-n1cc2cnc(NCC(F)(F)F)nc2c(-c2ccc(Br)cc2)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01595 BindingDB Entry DOI: 10.7270/Q28K7F57
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637537 ((3-amino-6-(2,2- difluorocyclopropyl)-1H- pyrazolo...) Show SMILES Cc1ncccc1C(=O)n1nc(N)c2ccc(nc12)C1CC1(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM507762 (7-chloro-4-(dimethylamino)-1-phenyl- quinazolin-2(...) Show SMILES CN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50604361 (CHEMBL5207874) Show SMILES CCOc1ccc2cn(-c3ccc4nn(C)cc4c3)c(=O)c(-c3ccc(Cl)cc3)c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01595 BindingDB Entry DOI: 10.7270/Q28K7F57
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637535 (US20230382911, Example 47 | [3-amino-6-(2,5-dihydr...) Show SMILES COc1c(F)cccc1C(=O)n1nc(N)c2ccc(nc12)C1=CCOC1 |t:24| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576002 (CHEMBL4590059) Show SMILES Cc1[nH]c2c(c(nn2c(=O)c1-c1ccc2ncccc2c1)-c1ccccc1)C1=CCCCC1 |t:32| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637563 ((3-amino-6-cyclopropyl-1H- pyrazolo[3,4-b]pyridin-...) Show SMILES COc1ncccc1C(=O)n1nc(N)c2ccc(nc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576020 (CHEMBL4529030) Show SMILES COc1ccc(cc1)-c1c(Nc2cnccn2)[nH]c2c(c(nn2c1=O)-c1ccccc1)C1=CCCCC1 |t:36| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637521 ((3-amino-6-((1RS,2RS)-2- methylcyclopropyl)-1H- py...) Show SMILES C[C@H]1C[C@@H]1c1ccc2c(N)nn(C(=O)c3ccccc3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637522 ((3-amino-6-((1RS,2RS)-2- methylcyclopropyl)-1H-pyr...) Show SMILES COc1ccccc1C(=O)n1nc(N)c2ccc(nc12)[C@H]1C[C@@H]1C |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637565 ((3-amino-6-cyclopropyl-1H- pyrazolo[3,4-b]pyridin-...) Show SMILES Nc1nn(C(=O)c2cccnc2C(F)(F)F)c2nc(ccc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50604354 (CHEMBL5185699) Show SMILES Cn1cnc2ccc(cc12)-n1cc2cnc(NCC(F)(F)F)nc2c(-c2ccc(Cl)cc2)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01595 BindingDB Entry DOI: 10.7270/Q28K7F57
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50604359 (CHEMBL5206988) Show SMILES Cn1cc2cc(ccc2n1)-n1cc2ccc(OCC(F)(F)F)nc2c(-c2ccc(Cl)cc2)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01595 BindingDB Entry DOI: 10.7270/Q28K7F57
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637528 ((3-amino-6-(2,2- difluorocyclopropyl)-1H- pyrazolo...) Show SMILES COc1ccccc1C(=O)n1nc(N)c2ccc(nc12)C1CC1(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637547 ((3RS,4RS)-4-(3-amino-6- cyclopropylpyrazolo[3,4- b...) Show SMILES C[C@@H]1[C@@H](CCNC1=O)C(=O)n1nc(N)c2ccc(nc12)C1CC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50576000 (CHEMBL4587880) Show SMILES Cc1[nH]c2c(c(nn2c(=O)c1-c1ccc(O)cc1)-c1ccccc1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01895 BindingDB Entry DOI: 10.7270/Q20R9T7P
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50604347 (CHEMBL5206904) Show SMILES CCNc1ncc2cn(-c3ccc(OC)cc3)c(=O)c(-c3ccc(Br)cc3)c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01595 BindingDB Entry DOI: 10.7270/Q28K7F57
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50604348 (CHEMBL5170690) Show SMILES COc1ccc(cc1)-n1cc2cnc(NCC(F)(F)F)nc2c(-c2ccc(Br)cc2)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01595 BindingDB Entry DOI: 10.7270/Q28K7F57
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637531 ((3-amino-6-((1rs,2RS,3SR)-2,3- dimethylcyclopropyl...) Show SMILES C[C@H]1[C@@H](C)[C@@H]1c1ccc2c(N)nn(C(=O)c3ccccc3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637540 ((3-amino-6-cyclopropyl-1H- pyrazolo[3,4-b]pyridin-...) Show SMILES C[C@H]1OCC[C@H]1C(=O)n1nc(N)c2ccc(nc12)C1CC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637540 ((3-amino-6-cyclopropyl-1H- pyrazolo[3,4-b]pyridin-...) Show SMILES C[C@H]1OCC[C@H]1C(=O)n1nc(N)c2ccc(nc12)C1CC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM637560 (3-(3-amino-6-cyclopropyl-1H- cyclopropyl-1H-pyrazo...) Show SMILES COc1c(cccc1C(=O)n1nc(N)c2ccc(nc12)C1CC1)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

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